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A:
I would use the following:
$entry = $v) {
$line.= sprintf('%s ', $v);
}
echo $line;
Silica nanoparticles change the biological properties of poly(lactide-co-glycolide).
Although silica nanoparticles (SiNPs) have the advantage of a higher loading capacity and a low cytotoxicity, their application has been hindered due to the weak adhesion of SiNPs to the polymer surfaces. In this study, SiNPs were covalently attached to a polymer surface and the adhesion of the SiNPs to poly(lactide-co-glycolide) (PLGA) as a medical implant material was evaluated. The SiNPs were synthesized by a sol-gel process and the attachment of the SiNPs to PLGA was achieved by click reaction between an azide group on the surface of SiNPs and an alkyne group on the surface of PLGA. The morphological analysis of SiNPs attached to PLGA was observed by scanning electron microscopy. The attachment of SiNPs to PLGA increased the hydrophilicity of PLGA. As a result, the temperature dependence of the viscoelasticity of PLGA-SiNPs blend was influenced. In addition, the compressive strength of PLGA-SiNPs blend decreased with the increased amount of SiNPs. However, the in vitro cell proliferation and viability were not significantly different between PLGA and PLGA-SiNPs. These results suggested that SiNPs affected the surface properties of PLGA and enhanced the hydrophilicity of PLGA, however, the SiNPs did not affect the biocompatibility of PLGA.
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